Description

2(1H)-Pyridinone, 1-(Trifluoroacetyl)- (9Ci) is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where the trifluoroacetyl group can impart desirable metabolic stability and bioavailability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides and fungicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in transition metal catalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or photophysical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Institutional R&D: A valuable reagent for methodological studies in organic chemistry, including new fluorination and heterocycle formation strategies.

Basic Information

Product Name	2(1H)-Pyridinone, 1-(Trifluoroacetyl)- (9Ci)
CAS No.	96254-06-7
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	1-(Trifluoroacetyl)-2(1H)-pyridinone; 1-(Trifluoroacetyl)pyridin-2(1H)-one; N-Trifluoroacetyl-2-pyridone; 2-Hydroxypyridine, 1-(trifluoroacetyl)-; 2-Pyridone, 1-(trifluoroacetyl)-; 1-Trifluoroacetyl-1,2-dihydropyridin-2-one; 96254-06-7 (CAS)
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyridinone, 1-(Trifluoroacetyl)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. While typically supplied as a research-grade chemical, specifications can be aligned with cGMP or other stringent quality standards for advanced development phases upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.