Description

(S)-Methyl 4-(Boc-Amino)-5-Tbdms-Pentanoate CAS NO 96014-55-0 is a high-purity, chiral protected amino acid derivative, essential for advanced organic synthesis. This compound serves as a critical, high-value building block for the controlled introduction of a specific stereocenter into complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of peptide-based therapeutics, active pharmaceutical ingredients (APIs), and other biologically active compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel peptide drugs, protease inhibitors, and other therapeutic agents.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a protected (S)-ornithine or related amino acid derivative.
• API Development: Serves as a crucial building block in the research and process development of new Active Pharmaceutical Ingredients (APIs), particularly in oncology and metabolic disease research.
• Chemical Biology Probes: Utilized in the creation of labeled or modified peptides for studying protein-protein interactions and enzyme mechanisms.
• Asymmetric Synthesis: Employed in catalytic asymmetric synthesis routes to construct complex natural products and chiral molecules.
• Custom Synthesis & Contract Manufacturing: A vital starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Item	Detail
Product Name	(S)-Methyl 4-(Boc-Amino)-5-Tbdms-Pentanoate
CAS No.	96014-55-0
Molecular Formula	C16H33NO4Si
Molecular Weight	331.53 g/mol
Synonyms	Methyl (S)-4-((tert-butoxycarbonyl)amino)-5-((tert-butyldimethylsilyl)oxy)pentanoate; (S)-Methyl 4-[(tert-Butoxycarbonyl)amino]-5-[(tert-Butyldimethylsilyl)oxy]pentanoate; Boc-Orn(Tbdms)-OMe; Boc-L-Orn(TBDMS)-OMe; Nα-Boc-Nδ-(TBDMS)-L-ornithine methyl ester; (S)-Methyl 5-((tert-butyldimethylsilyl)oxy)-4-((tert-butoxycarbonyl)amino)pentanoate
EINECS	Contact for details

Quality Control

Our (S)-Methyl 4-(Boc-Amino)-5-Tbdms-Pentanoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, chiral purity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP environments for non-GMP starting materials and support global regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.