Description

3-Oxo-4-(Phenylmethoxy)-Butanoic Acid 1,1-Dimethylethyl Ester is a high-purity, protected β-keto ester derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in providing a reactive ketone functionality adjacent to an ester group, protected by a benzyl ether, enabling precise and controlled chemical transformations. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for constructing complex molecular scaffolds, heterocycles, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Utilized in Claisen condensations, Michael additions, and other C-C bond-forming reactions to construct complex organic frameworks.
• Peptidomimetic Research: Serves as a precursor for non-natural amino acids and peptide analogs in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides and herbicides.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in chemistry laboratories.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high-purity intermediates.

Basic Information

Product Name	3-Oxo-4-(Phenylmethoxy)-Butanoic Acid 1,1-Dimethylethyl Ester
CAS No.	95967-46-7
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	tert-Butyl 3-oxo-4-(benzyloxy)butanoate; 4-(Benzyloxy)-3-oxobutanoic Acid tert-Butyl Ester; Butanoic acid, 3-oxo-4-(phenylmethoxy)-, 1,1-dimethylethyl ester; tert-Butyl 4-(benzyloxy)-3-oxobutanoate; 95967-46-7; 3-Oxo-4-(benzyloxy)butyric acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-Oxo-4-(Phenylmethoxy)-Butanoic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.