Description

7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials, where its unique fused dioxino-pyridine scaffold introduces specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
CAS No.	95897-49-7
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	7-Bromo-2,3-dihydro-1,4-dioxino[2,3-b]pyridine; 1,4-Dioxino[2,3-b]pyridine, 7-bromo-2,3-dihydro-; 7-Bromo-2,3-dihydro[1,4]dioxino[2,3-b]pyridine; 95897-49-7; 7-Bromodioxinopyridine; 7-Bromo-2,3-dihydro-1,4-dioxino[2,3-b]pyridin; 7-Bromo-2,3-dihydro[1,4]dioxino[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP (current Good Manufacturing Practice) compliance for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.