Description

6-Hydroxynicotinonitrile is a versatile heterocyclic building block and key pharmaceutical intermediate. This compound matters for its crucial role in synthesizing complex molecules, particularly in medicinal chemistry and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing nicotinamide and pyridine derivatives.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing nicotinamide or substituted pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed reactions.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Biochemical Research: Useful as a building block for synthesizing enzyme inhibitors or probes targeting NAD(P)-dependent enzymes.
• Fine Chemical Production: A versatile intermediate for manufacturing specialty chemicals and dyes.

Basic Information

Item	Details
Product Name	6-Hydroxynicotinonitrile
CAS No.	95891-30-8
Molecular Formula	C6H4N2O
Molecular Weight	120.11 g/mol
Synonyms	6-Hydroxypyridine-3-carbonitrile; 3-Cyano-6-hydroxypyridine; 6-Hydroxy-3-cyanopyridine; 6-Hydroxynicotinamide nitrile; 6-Hydroxy-3-pyridinecarbonitrile; 5-Cyano-2-pyridinol; 2-Hydroxy-5-cyanopyridine
EINECS	Contact for details

Quality Control

Our 6-Hydroxynicotinonitrile is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.