Description

2-Hydroxyisonicotinonitrile is a versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its functionalized pyridine core, which enables its use in constructing complex molecular architectures for advanced research and development. It is primarily utilized by pharmaceutical researchers and agrochemical scientists in the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized nicotinamide or pyridine motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology Probes: Useful for synthesizing molecular probes and inhibitors for studying enzymatic activity and biological pathways.
• Fine Chemical Production: Acts as a building block for the manufacture of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Hydroxyisonicotinonitrile
CAS No.	95891-29-5
Molecular Formula	C6H4N2O
Molecular Weight	120.11 g/mol
Synonyms	2-Hydroxy-4-cyanopyridine; 4-Cyano-2-pyridinol; 2-Hydroxypyridine-4-carbonitrile; 4-Cyano-2-hydroxypyridine; 2-Pyridinol, 4-cyano-; Isonicotinonitrile, 2-hydroxy-; 2-Hydroxy-isonicotinonitrile; 2(1H)-Pyridinone, 4-cyano-
EINECS	Contact for details

Quality Control

Our 2-Hydroxyisonicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.