Description

3-Chloro-5-Methoxypyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and methoxy substituents, enables precise molecular modifications essential for developing high-value compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and kinase inhibitors.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to create complex ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Intermediate in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for designing molecular probes and diagnostic agents in biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Product Name	3-Chloro-5-Methoxypyridine
CAS No.	95881-83-7
Molecular Formula	C6H6ClNO
Molecular Weight	143.57 g/mol
Synonyms	5-Methoxy-3-chloropyridine; 3-Chloro-5-methoxypyridine; 3-Chloro-5-pyridinol methyl ether; 95881-83-7; 3-Chloro-5-methoxy-pyridine; Pyridine, 3-chloro-5-methoxy-
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.