Description

Kadsurenone is a bioactive lignan compound isolated from the *Piper kadsuma* plant. This compound is of significant interest for its role as a selective antagonist of platelet-activating factor (PAF), making it a valuable research tool in pharmacological and biochemical studies. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and academic sectors for investigating inflammatory pathways, receptor binding studies, and as a lead compound for novel therapeutic development.

Application

• Pharmacological Research: Used as a selective PAF receptor antagonist to study inflammatory and allergic response mechanisms.
• Biochemical Assay Development: Serves as a reference standard and active control in the development of assays targeting PAF-mediated pathways.
• Lead Compound Optimization: Acts as a structural template for the design and synthesis of novel anti-inflammatory or anti-thrombotic agents.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental research in cell signaling and mediator biology.
• Pharmaceutical R&D: Utilized in drug discovery programs focused on modulating the PAF pathway for potential therapeutic applications.
• Reference Material: Provides a high-purity standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	Kadsurenone
CAS No.	95851-37-9
Molecular Formula	C20H20O6
Molecular Weight	356.37 g/mol
Synonyms	(+)-Kadsurenone; Lignan F; 5-[(3S,3aR,6S,6aR)-6-(1,3-Benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-1,3-benzodioxole; Piper kadsuma lignan; PAF antagonist
EINECS	Contact for details

Quality Control

Our Kadsurenone is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.