Description

Phyllanthin CAS NO 10351-88-9 is a major bioactive lignan compound primarily isolated from the plant *Phyllanthus amarus*. It serves as a key analytical reference standard and a critical starting material for research into hepatoprotective and metabolic activities. This high-purity compound is essential for pharmaceutical R&D, nutraceutical standardization, and advanced phytochemical studies. We supply it with guaranteed batch-to-batch consistency to support your most demanding development projects.

Application

• Pharmaceutical Reference Standard: Used as a primary chemical marker for the standardization, quality control, and authentication of herbal extracts and finished products derived from *Phyllanthus* species.
• Bioactivity and Pharmacological Research: Serves as a crucial investigational compound in preclinical studies targeting liver health, including research on hepatoprotective, anti-hepatitis, and anti-inflammatory mechanisms.
• Nutraceutical and Herbal Supplement Formulation: Employed in the development and standardization of high-value herbal supplements where consistent phyllanthin content is a key quality and efficacy parameter.
• Analytical Method Development: Essential for developing and validating precise analytical methods such as HPLC, HPTLC, and LC-MS for the quantification of lignans in complex botanical matrices.
• Academic and Institutional Research: Used in universities and research institutes for studies in phytochemistry, natural product chemistry, and metabolic pathway analysis.
• Cosmeceutical Applications: Investigated for potential use in advanced skincare formulations due to its antioxidant and anti-inflammatory properties.

Basic Information

Item	Detail
Product Name	Phyllanthin
CAS No.	10351-88-9
Molecular Formula	C24H34O6
Molecular Weight	418.53 g/mol
Synonyms	Phyllanthin; (-)-Phyllanthin; NSC 329700; (7R,8S,7'R,8'S)-4,4',9,9'-Tetramethoxy-7,7'-epoxylignan; 3,4-Dimethoxyphenyl 3-(3,4-dimethoxyphenyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-carboxylate; Lignan F; 1,3-Benzodioxole, 5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-, (1S,3aR,4S,6aR)-rel-
EINECS	Contact for details

Quality Control

Every batch of Phyllanthin is manufactured and analyzed under strict quality management protocols. Our standard grade typically meets a purity specification of ≥95% to ≥98% (by HPLC), ensuring it is suitable for demanding research and development applications. Identity is confirmed via spectroscopic methods including IR and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and analytical results is provided with each shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥95.0% - 98.0%
Related Substances (HPLC)	Total impurities ≤5.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.