Description

Podophyllic is a specialized organic compound derived from podophyllotoxin, a key lignan found in the *Podophyllum* species. This compound is of significant interest in the pharmaceutical and fine chemical industries due to its role as a crucial intermediate in the synthesis of potent chemotherapeutic agents. It is primarily sought by research institutions and manufacturers engaged in developing and producing anti-cancer drugs, particularly etoposide and teniposide.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the multi-step synthesis of semi-synthetic chemotherapeutic drugs like etoposide and teniposide.
• Oncology Research: Used in biochemical and pharmacological research to study structure-activity relationships (SAR) of podophyllotoxin derivatives and develop novel anti-mitotic agents.
• Fine Chemical Synthesis: Employed in organic synthesis laboratories for the preparation of complex, biologically active molecules and for exploring new synthetic pathways.
• Reference Standard: Serves as a high-purity analytical reference standard in quality control (QC) and research & development (R&D) laboratories for method development and validation.

Basic Information

Product Name	Podophyllic
CAS No.	1853-37-8
Molecular Formula	C22H22O8
Molecular Weight	414.41 g/mol
Synonyms	Podophyllic Acid; Podophyllic Acid Lactone; 4'-Demethylepipodophyllotoxin; 4'-Demethyl-9-epipodophyllotoxin; 4'-Demethylepipodophyllotoxin 9-carboxylic Acid Lactone; NSC 33410; 9-Epi-4'-demethylpodophyllotoxin; 4'-Desmethylepipodophyllotoxin
EINECS	Contact for details

Quality Control

Our Podophyllic is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency suitable for pharmaceutical research and synthesis. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material that meets the stringent requirements for use as a pharmaceutical intermediate or analytical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.