Description

1-Thia-5-Azaspiro[3.4]Octane-6-Thione, 2,2,3,3,5-Pentamethyl- is a specialized spirocyclic thiourea derivative, a high-value synthetic intermediate prized for its unique constrained molecular architecture. This compound matters for its role as a key building block in advanced pharmaceutical and agrochemical research, enabling the synthesis of novel molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its spirocyclic structure can contribute to unique modes of action and improved environmental profiles.
• Ligand Synthesis in Catalysis: Acts as a precursor for creating specialized thiourea-based ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the development of advanced organic materials, including polymers and liquid crystals, where its rigid structure can influence material properties.
• Chemical Biology Probe Development: Utilized as a core structure for designing molecular probes to study enzyme function and protein-ligand interactions.

Basic Information

Product Name	1-Thia-5-Azaspiro[3.4]Octane-6-Thione, 2,2,3,3,5-Pentamethyl-
CAS No.	95765-62-1
Molecular Formula	C10H17NS2
Molecular Weight	215.38 g/mol
Synonyms	2,2,3,3,5-Pentamethyl-1-thia-5-azaspiro[3.4]octane-6-thione; Pentamethyl-1-thia-5-azaspiro[3.4]octane-6-thione; 1-Thia-5-azaspiro[3.4]octane-6-thione, pentamethyl-; Spirocyclic thiourea derivative; CAS 95765-62-1
EINECS	Contact for details

Quality Control

Our production of 1-Thia-5-Azaspiro[3.4]Octane-6-Thione, 2,2,3,3,5-Pentamethyl- adheres to strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.