Description

Nedaplatin is a second-generation platinum-based antineoplastic agent, representing a significant advancement in chemotherapeutic drug development. Its primary value lies in its improved therapeutic profile and reduced nephrotoxicity compared to earlier cisplatin derivatives, offering a critical tool for oncology treatment regimens. This high-purity active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers and research institutions developing and producing targeted cancer therapies.

Application

• Oncological Pharmaceutical Manufacturing: As a key active pharmaceutical ingredient (API) in the formulation of injectable chemotherapeutic drugs for the treatment of various cancers.
• Head and Neck Cancer Therapy: A primary chemotherapeutic agent, often used in combination with radiotherapy, for the treatment of squamous cell carcinoma of the head and neck.
• Lung Cancer Treatment: Used in chemotherapy regimens for non-small cell lung cancer (NSCLC), demonstrating efficacy in clinical settings.
• Esophageal Cancer: Employed in therapeutic protocols for esophageal carcinoma, contributing to improved patient outcomes.
• Clinical Research & Development: Serves as a reference standard and key component in preclinical and clinical studies for novel cancer treatment combinations and delivery mechanisms.
• Generic Drug Production: A critical raw material for manufacturers producing generic versions of established nedaplatin-based oncology medications.

Basic Information

Product Name	Nedaplatin
CAS No.	95734-82-0
Molecular Formula	C₂H₈N₂O₃Pt
Molecular Weight	303.18 g/mol
Synonyms	(Glycolato-O,O')diammineplatinum(II); cis-Amminedichloro(2-hydroxyacetato-O,O')platinum; cis-Diammine(glycolato)platinum; cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) (common mis-association); Nedaplatine; Aqupla® (Brand Name); 254-S; CDGP
EINECS	Contact for details

Quality Control

Our Nedaplatin is manufactured under strict quality management systems to meet the rigorous standards required for pharmaceutical active ingredients. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with cGMP and relevant pharmacopoeial guidelines for API production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.