Description

5-(Trifluoromethyl)Picolinonitrile is a high-value fluorinated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique trifluoromethyl and nitrile functional groups make it an essential building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Intermediate for synthesizing functionalized polymers and advanced organic electronic materials.
• Fluorine Chemistry Studies: A valuable substrate for investigating novel fluorination reactions and the influence of fluorine atoms on molecular properties.

Basic Information

Product Name	5-(Trifluoromethyl)Picolinonitrile
CAS No.	95727-86-9
Molecular Formula	C7H3F3N2
Molecular Weight	172.11 g/mol
Synonyms	2-Cyano-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 5-(trifluoromethyl)-; 5-Trifluoromethylpicolinonitrile; 5-Trifluoromethyl-2-cyanopyridine; 2-Cyano-5-trifluoromethylpyridine; Picolinonitrile, 5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Picolinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.