Description

α-D-Galactopyranuronic Acid, 1,2,3,4-Tetraacetate is a key acetylated derivative of galacturonic acid, serving as a vital protected intermediate in synthetic carbohydrate chemistry. This compound is essential for researchers and manufacturers requiring precise control over glycosidic bond formation and oligosaccharide synthesis. It is primarily utilized in the pharmaceutical, biotechnology, and advanced materials sectors for the development of novel therapeutics, diagnostic agents, and functional biomaterials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex carbohydrate-based drugs, including anticoagulants, anti-inflammatory agents, and cancer therapeutics.
• Glycobiology Research: Used in the enzymatic and chemical synthesis of oligosaccharides and glycoconjugates for studying cell signaling, immune response, and pathogen recognition.
• Bioconjugate Chemistry: Serves as a precursor for creating targeted drug delivery systems, vaccine adjuvants, and diagnostic imaging probes through conjugation with proteins or nanoparticles.
• Material Science: Employed in the development of functional polymers, hydrogels, and surface coatings with specific bio-adhesive or recognition properties.
• Enzyme Substrate: Acts as a substrate or inhibitor in assays for enzymes like glycosyltransferases, glycosidases, and carbohydrate-processing enzymes.
• Standards and Reference Material: Provides a high-purity standard for analytical method development and quality control in carbohydrate analysis (HPLC, MS, NMR).

Basic Information

Product Name	α-D-Galactopyranuronic Acid, 1,2,3,4-Tetraacetate
CAS No.	95722-13-7
Molecular Formula	C14H18O11
Molecular Weight	362.28 g/mol
Synonyms	1,2,3,4-Tetra-O-acetyl-α-D-galactopyranuronic acid; α-D-Galacturonic acid 1,2,3,4-tetraacetate; Tetra-O-acetyl-α-D-galactopyranuronic acid; Acetylated D-galacturonic acid; Galacturonic acid tetraacetate; α-D-GalUA(Ac)4; (2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(carboxy)oxan-2-yl acetate
EINECS	Contact for details

Quality Control

Our α-D-Galactopyranuronic Acid, 1,2,3,4-Tetraacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Rotation [α]²⁰D	+80° to +90° (c=1 in CHCl₃)
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.