Description

Diendo-3-Amino-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester is a specialized bicyclic amino acid ester derivative, serving as a high-value chiral building block in advanced organic synthesis. Its constrained, rigid bicyclo[2.2.1]heptane (norbornane) framework and functionalized amino acid side chain make it a critical precursor for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients, chiral ligands, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides with specific stereochemical activity.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing sophisticated chiral ligands used in asymmetric catalysis.
• Peptidomimetics & Constrained Peptide Design: The bicyclic structure is incorporated to create conformationally restricted peptide analogs for biological studies.
• Material Science Research: Employed in the development of specialty polymers and functional organic materials with unique properties.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and stereoselective synthesis.

Basic Information

Product Name	Diendo-3-Amino-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester
CAS No.	95630-77-6
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	Ethyl 3-Amino-2-norbornanecarboxylate (endo isomer); Di-endo-3-Aminobicyclo[2.2.1]heptane-2-carboxylic Acid Ethyl Ester; 3-Amino-2-norbornanecarboxylic Acid Ethyl Ester; 2-Norbornanecarboxylic acid, 3-amino-, ethyl ester, endo-; Ethyl 3-aminobicyclo[2.2.1]heptane-2-carboxylate; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-amino-, ethyl ester, (1R,2S,3R,4S)-rel-; (1R,2S,3R,4S)-rel-3-Aminobicyclo[2.2.1]heptane-2-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Diendo-3-Amino-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (di-endo isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.