Description

n-Me-Thr-Ome·Hcl CAS NO 95599-23-8 is a protected amino acid derivative, specifically the methyl ester hydrochloride salt of N-methyl-L-threonine. This compound serves as a crucial high-purity building block in advanced organic synthesis, enabling the controlled introduction of a modified threonine moiety. It is primarily utilized by pharmaceutical researchers and peptide chemists for the development of novel therapeutic peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key raw material in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid derivative to incorporate N-methyl-threonine residues.
• Medicinal Chemistry Research: Serves as a building block for creating libraries of novel compounds in drug discovery programs.
• Bioconjugation: Potential use in the modification of proteins or other biomolecules to alter their properties or create targeted drug conjugates.
• Chemical Biology Probes: Useful for synthesizing probes to study enzyme function, protein-protein interactions, and cellular processes.
• Process Development: Employed in the scale-up and optimization of synthetic routes for peptide therapeutics.

Basic Information

Item	Detail
Product Name	n-Me-Thr-Ome·Hcl
CAS No.	95599-23-8
Molecular Formula	C6H14ClNO3
Molecular Weight	183.63 g/mol
Synonyms	N-Methyl-L-threonine methyl ester hydrochloride; (2S,3R)-2-(Methylamino)-3-hydroxybutanoic acid methyl ester hydrochloride; Methyl (2S,3R)-2-(methylamino)-3-hydroxybutanoate hydrochloride; L-Threonine, N-methyl-, methyl ester, hydrochloride; Methyl N-methylthreoninate hydrochloride; N-Me-Thr-OMe·HCl
EINECS	Contact for details

Quality Control

Our n-Me-Thr-Ome·Hcl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.