Description

(-)-Ethyl-(R)-2-Hydroxy-4-Cyclohexylbutyrate is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. This compound is valued for its defined stereochemistry, which is crucial for imparting specific biological activity and physical properties in final products. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly those targeting cardiovascular and central nervous system disorders.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysis, enabling highly selective chemical transformations.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex molecules in agrochemicals, flavors, and fragrances.
• Academic & Process Chemistry Research: Employed in methodological development and scale-up studies for new synthetic routes.
• Material Science: Potential monomer or modifier for creating polymers with specific chiral or structural properties.

Basic Information

Product Name	(-)-Ethyl-(R)-2-Hydroxy-4-Cyclohexylbutyrate
CAS No.	95500-39-3
Molecular Formula	C₁₂H₂₂O₃
Molecular Weight	214.30 g/mol
Synonyms	(R)-Ethyl 2-Hydroxy-4-cyclohexylbutanoate; Ethyl (2R)-2-Hydroxy-4-cyclohexylbutyrate; (R)-(-)-Ethyl 2-Hydroxy-4-cyclohexylbutyrate; (R)-2-Hydroxy-4-cyclohexylbutyric Acid Ethyl Ester; (-)-Ethyl (R)-2-Hydroxy-4-cyclohexylbutanoate; (R)-Ethyl 2-Hydroxy-4-cyclohexylbutyrate; 95500-39-3; Ethyl (R)-2-Hydroxy-4-cyclohexylbutyrate
EINECS	Contact for details

Quality Control

Our (-)-Ethyl-(R)-2-Hydroxy-4-Cyclohexylbutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]²⁰D	-10° to -12° (c=1 in CHCl₃)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.