Description

4-Azaspiro[2.4]heptane is a specialized nitrogen-containing spirocyclic compound that serves as a valuable and versatile building block in advanced organic synthesis. Its unique bridged bicyclic structure makes it a critical intermediate for constructing complex molecular architectures with high three-dimensional complexity. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Scaffold: Used to introduce conformational rigidity and explore novel pharmacophore space in lead optimization programs.
• Agrochemical Synthesis: Intermediate in the development of new pesticides and herbicides with unique modes of action.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme function.
• Material Science Research: Potential monomer or precursor for novel polymers and functional materials with specific properties.

Basic Information

Product Name	4-Azaspiro[2.4]heptane
CAS No.	95442-76-5
Molecular Formula	C6H11N
Molecular Weight	97.16 g/mol
Synonyms	1-Azaspiro[2.3]hexane; Spiro[cyclopropane-1,2'-pyrrolidine]; 2,5-Diazabicyclo[2.2.1]heptane (related bicyclic system); 4-Azaspiro[2.4]heptane; 1-Aza-4-spiro[2.4]heptane; 4-Aza-1-spiro[2.4]heptane; NSC 405124; Pyrrolidine, 1,1-cyclopropyl-
EINECS	Contact for details

Quality Control

Our 4-Azaspiro[2.4]heptane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. We adhere to cGMP principles where applicable to support our customers' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.