Description

(-)-Benzylmethylphenylsilylacetic Acid CAS NO 95349-35-2 is a high-purity, chiral organosilicon compound featuring a carboxylic acid functional group. This specialized chemical serves as a valuable building block and chiral auxiliary in advanced organic synthesis, enabling the creation of stereochemically defined molecules. It is primarily utilized by pharmaceutical research and fine chemical sectors for the development of active pharmaceutical ingredients (APIs) and complex organic materials.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for constructing stereocenters in drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis Reagent: Used as a chiral auxiliary or ligand to induce enantioselectivity in catalytic reactions.
• Advanced Material Research: Employed in the development of novel silicon-containing polymers and functional materials.
• Organic Methodology Development: Serves as a model substrate for developing new silylation and cross-coupling reactions in academic and industrial R&D.
• Protecting Group Chemistry: The silyl group can act as a protecting group for alcohols or other sensitive functionalities during multi-step syntheses.

Basic Information

Item	Details
Product Name	(-)-Benzylmethylphenylsilylacetic Acid
CAS No.	95349-35-2
Molecular Formula	C16H18O2Si
Molecular Weight	270.40 g/mol
Synonyms	(S)-(-)-Benzylmethylphenylsilylacetic Acid; (S)-α-(Benzylmethylphenylsilyl)acetic Acid; (S)-BMPSA; (-)-BMPSA; (S)-Benzyl(methyl)phenylsilylacetic Acid; (S)-2-(Benzylmethylphenylsilyl)acetic Acid; (S)-Carboxymethyl(benzyl)methylphenylsilane
EINECS	Contact for details

Quality Control

Our production of (-)-Benzylmethylphenylsilylacetic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including HPLC, chiral GC, and NMR spectroscopy. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.