Description

Ethyl (R)-(+)-4-Bromo-3-Hydroxybutyrate is a high-purity chiral building block of significant importance in asymmetric synthesis. This compound is valued for its role as a key intermediate in the production of optically active pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of statin drugs (e.g., cholesterol-lowering agents) and other bioactive molecules.
• Asymmetric Synthesis: Used in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Serves as a building block for developing chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and catalysis studies.

Basic Information

Product Name	Ethyl (R)-(+)-4-Bromo-3-Hydroxybutyrate
CAS No.	95310-94-4
Molecular Formula	C6H11BrO3
Molecular Weight	211.06 g/mol
Synonyms	(R)-Ethyl 4-Bromo-3-hydroxybutyrate; (R)-(+)-4-Bromo-3-hydroxybutyric Acid Ethyl Ester; Ethyl (R)-4-Bromo-3-hydroxybutanoate; (R)-BHBE; (3R)-4-Bromo-3-hydroxybutyric Acid Ethyl Ester; (R)-Ethyl 4-Bromo-3-hydroxybutanoate; (R)-4-Bromo-3-hydroxybutyric Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl (R)-(+)-4-Bromo-3-Hydroxybutyrate is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity suitable for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and cGMP starting material production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Specific Rotation	+20° to +24° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.