Description

4-Spiro-[1-(3,4-Dihydro)Naphthalene] Piperidine Hcl is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular research. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a critical starting material for scaling up synthetic routes under GMP conditions.
• Academic & Contract Research: Employed in university and CRO settings for exploring new synthetic methodologies and biological targets.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and validation.

Basic Information

Product Name	4-Spiro-[1-(3,4-Dihydro)Naphthalene] Piperidine Hcl
CAS No.	95195-98-5
Molecular Formula	C15H19N·HCl
Molecular Weight	249.78 g/mol
Synonyms	4-Spiro(1,2,3,4-tetrahydronaphthalene-1,4'-piperidine) hydrochloride; 1',2',3',4'-Tetrahydrospiro[piperidine-4,1'-naphthalene] hydrochloride; 4-(1,2,3,4-Tetrahydronaphthalen-1-yl)piperidine hydrochloride; 1-(1,2,3,4-Tetrahydronaphthalen-1-yl)piperidin-4-ol hydrochloride (tautomer); Spiro[piperidine-4,1'(1'H)-naphthalene] hydrochloride; 95195-98-5; 4-Spiro(1,2,3,4-tetrahydronaphthalen-1,4-piperidine) HCl
EINECS	Contact for details

Quality Control

Our 4-Spiro-[1-(3,4-Dihydro)Naphthalene] Piperidine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.