Description

1H-Thieno(3,4-D)Imidazole-4-Pentanoic Acid, Hexahydro-2-Oxo-, 4-Nitrophenyl Ester, (3aS,4S,6aR)- is a specialized, high-purity chemical intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex pharmaceutical molecules and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in the synthesis of novel therapeutic agents.

Application

This advanced intermediate is utilized in a variety of sophisticated synthetic pathways, including:

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic platforms.
• Proteomics Research: Serves as a reagent or building block in the study of protein interactions and enzyme mechanisms.
• Peptidomimetic Synthesis: Employed in the design and construction of peptide-like molecules with enhanced stability and bioavailability.
• Agrochemical Development: Acts as a key intermediate in the research and production of new-generation pesticides and herbicides.
• Academic & Industrial R&D: Essential for method development and exploratory chemistry in both university laboratories and corporate R&D centers.

Basic Information

Product Name	1H-Thieno(3,4-D)Imidazole-4-Pentanoic Acid, Hexahydro-2-Oxo-, 4-Nitrophenyl Ester, (3aS,4S,6aR)-
CAS No.	95114-52-6
Molecular Formula	C16H17N3O5S
Molecular Weight	363.39 g/mol
Synonyms	(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid 4-nitrophenyl ester; Biotin 4-nitrophenyl ester; Biotin p-nitrophenyl ester; (+)-Biotin 4-nitrophenyl ester; D-Biotin p-nitrophenyl ester; Vitamin H p-nitrophenyl ester; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid 4-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our 1H-Thieno(3,4-D)Imidazole-4-Pentanoic Acid, Hexahydro-2-Oxo-, 4-Nitrophenyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.