Description

4-Azido-5-Iodoclebopride is a specialized, high-value chemical intermediate designed for advanced research and development. This compound is critical for scientists working on novel molecular probes and radiopharmaceutical precursors, particularly in the field of positron emission tomography (PET) imaging. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) focused on neuroscience and oncology.

Application

• PET Tracer Development: A key precursor for the synthesis of radiolabeled clebopride analogs used in neuroimaging studies.
• Dopamine Receptor Research: Serves as a versatile intermediate for creating molecular probes targeting D2/D3 dopamine receptors.
• Click Chemistry Substrate: The azido functional group enables its use in bioorthogonal conjugation and labeling applications.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to develop new central nervous system (CNS) active compounds.
• Chemical Biology: Employed in the design of activity-based probes for studying enzyme function and protein interactions.

Basic Information

Product Name	4-Azido-5-Iodoclebopride
CAS No.	94978-71-9
Molecular Formula	C20H23ClIN6O2
Molecular Weight	541.80 g/mol
Synonyms	4-Azido-5-iodo-clebo; 4-Azido-5-iodoclebopride; 5-Iodo-4-azidoclebopride; Clebopride, 4-azido-5-iodo-; N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-azido-4-iodo-2-methoxybenzamide; 2-Methoxy-N-[(1-allyl-2-pyrrolidinyl)methyl]-5-azido-4-iodobenzamide; 4-Azido-5-iodo-2-methoxy-N-[(1-allyl-2-pyrrolidinyl)methyl]benzamide
EINECS	Contact for details

Quality Control

Every batch of 4-Azido-5-Iodoclebopride is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We provide full traceability and Certificates of Analysis (COA) detailing purity, identity, and impurity profiles via HPLC, NMR, and mass spectrometry. Our quality commitment ensures material integrity for sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at -20°C or below to minimize degradation. This material is strictly light-sensitive and easily oxidized; prolonged exposure to air, light, or ambient temperature should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.