Description

1-o-Acetyl-2,3,4,6-Tetra-o-Benzyl-D-Mannopyranose is a key protected monosaccharide derivative, specifically a fully benzylated mannose intermediate with a single acetyl group at the anomeric position. This compound is critically important as a versatile and highly reactive building block for the stereoselective synthesis of complex oligosaccharides and glycoconjugates. It is primarily needed by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, glycobiology research, and the development of novel therapeutics, diagnostics, and vaccines.

Application

• Glycosylation Reagent: Serves as a crucial mannosyl donor in chemical glycosylation reactions for constructing α-linked mannose-containing oligosaccharides.
• Pharmaceutical Intermediate: Used in the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and investigational new drugs.
• Glycoconjugate Synthesis: A foundational precursor for creating glycopeptides, glycolipids, and other biologically active glycoconjugates.
• Carbohydrate Chemistry Research: Essential for academic and industrial research exploring new synthetic methodologies and carbohydrate-protein interactions.
• Diagnostic Reagent Development: Employed in the production of carbohydrate antigens and probes used in diagnostic assays and imaging.
• Vaccine Adjuvant Research: Investigated as a component in the synthesis of synthetic carbohydrate antigens for conjugate vaccine development.

Basic Information

Product Name	1-o-Acetyl-2,3,4,6-Tetra-o-Benzyl-D-Mannopyranose
CAS No.	94943-10-9
Molecular Formula	C34H34O7
Molecular Weight	554.63 g/mol
Synonyms	2,3,4,6-Tetra-O-benzyl-α-D-mannopyranosyl acetate; 1-O-Acetyl-2,3,4,6-tetra-O-benzyl-α-D-mannopyranose; Tetra-O-benzyl-α-D-mannopyranosyl acetate; Acetyl tetra-O-benzyl-α-D-mannopyranoside; α-D-Mannopyranose, 1-acetate, 2,3,4,6-tetrakis-O-(phenylmethyl)-; 1-Acetyl-2,3,4,6-tetra-O-benzyl-α-D-mannopyranose
EINECS	Contact for details

Quality Control

Our 1-o-Acetyl-2,3,4,6-Tetra-o-Benzyl-D-Mannopyranose is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for advanced synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and optical rotation analysis, to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a desiccator or under an inert atmosphere for long-term storage to maintain optimal stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.