Description

1,3-Dimethyl-4-(Trifluoromethyl)-1,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is a high-value, heterocyclic organic compound featuring a fused pyrazolo-pyridinone core substituted with a trifluoromethyl group. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology, neurology, and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and library synthesis due to its privileged pyrazolo[3,4-b]pyridine scaffold and the bioisosteric properties of the trifluoromethyl group.
• Agrochemical Research: Serves as a core structure for developing new active ingredients for crop protection, such as herbicides and insecticides.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Organic Synthesis Reagent: Employed in specialized organic synthesis for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	1,3-Dimethyl-4-(Trifluoromethyl)-1,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One
CAS No.	94835-66-2
Molecular Formula	C10H8F3N3O
Molecular Weight	243.19 g/mol
Synonyms	1,3-Dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one; 4-(Trifluoromethyl)-1,3-dimethyl-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 1,3-Dimethyl-4-trifluoromethyl-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 6H-Pyrazolo[3,4-b]pyridin-6-one, 1,3-dimethyl-4-(trifluoromethyl)-1,7-dihydro-; Pyrazolo[3,4-b]pyridine intermediate 94835-66-2
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-4-(Trifluoromethyl)-1,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.