Description

2,5-Piperidinedicarboxylic Acid, 1-(3-Mercapto-1-Oxopropyl)-, cis- is a specialized chiral piperidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both dicarboxylic acid and protected mercapto functionalities, makes it a valuable intermediate for constructing complex molecules with high stereochemical control. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and catalyst development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific cis-configuration is crucial for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The piperidine scaffold is integral in designing peptidomimetic compounds for drug discovery programs.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes to study enzyme mechanisms and protein interactions, leveraging the reactive thiol group.

Basic Information

Product Name	2,5-Piperidinedicarboxylic Acid, 1-(3-Mercapto-1-Oxopropyl)-, cis-
CAS No.	94769-32-1
Molecular Formula	C10H15NO5S
Molecular Weight	261.30 g/mol
Synonyms	cis-1-(3-Mercapto-1-oxopropyl)-2,5-piperidinedicarboxylic acid; (2S,5S)-1-(3-Mercaptopropanoyl)piperidine-2,5-dicarboxylic acid; 1-(3-Mercaptopropionyl)piperidine-2,5-dicarboxylic acid (cis); NSC 339586; 2,5-Piperidinedicarboxylic acid, 1-(3-mercapto-1-oxopropyl)-, (2S,5S)-; L,L-cis-1-(3-Mercaptopropionyl)piperidine-2,5-dicarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2,5-Piperidinedicarboxylic Acid, 1-(3-Mercapto-1-Oxopropyl)-, cis- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (cis-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.