Description

Ethyl 3,3,3-Trifluoro-2-Hydroxy-Propionate is a high-value fluorinated building block characterized by its trifluoromethyl and hydroxyl functional groups. This compound is essential for synthesizing advanced molecules where the introduction of fluorine atoms is required to modulate properties like metabolic stability, lipophilicity, and bioavailability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated analogs of drug candidates, particularly in protease inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides where fluorine substitution enhances activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Advanced Polymer Modifiers: Incorporated to introduce fluorine into polymer side chains, enhancing material properties like solvent resistance and lowering surface energy.
• Organic Synthesis Building Block: Utilized in asymmetric synthesis and cross-coupling reactions to construct complex, fluorinated molecular architectures.

Basic Information

Product Name	Ethyl 3,3,3-Trifluoro-2-Hydroxy-Propionate
CAS No.	94726-00-8
Molecular Formula	C5H7F3O3
Molecular Weight	172.10 g/mol
Synonyms	Ethyl 3,3,3-Trifluoro-2-Hydroxypropionate; 2-Hydroxy-3,3,3-trifluoropropionic Acid Ethyl Ester; 3,3,3-Trifluoro-2-hydroxypropionic Acid Ethyl Ester; Ethyl 3,3,3-Trifluorolactate; Trifluorolactic Acid Ethyl Ester; Ethyl α-Hydroxy-β,β,β-trifluoropropionate; NSC 403058; F3CCH(OH)COOEt
EINECS	Contact for details

Quality Control

Our Ethyl 3,3,3-Trifluoro-2-Hydroxy-Propionate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.