Description

3,4,6-Tri-o-Acetyl-2-Azido-2-Deoxy-β-D-Glucopyranosyl Trichloroacetimidate is a sophisticated glycosyl donor, a key building block in carbohydrate and glycoconjugate chemistry. Its value lies in its high reactivity and stereoselectivity, enabling the efficient synthesis of complex oligosaccharides and glycoconjugates. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel glycomimetics, vaccines, and diagnostic agents.

Application

• Glycosylation Reactions: As a highly reactive glycosyl donor for the stereoselective synthesis of β-glycosidic linkages.
• Oligosaccharide Synthesis: A critical intermediate in the automated and manual assembly of complex carbohydrate chains for research and drug discovery.
• Pharmaceutical Intermediates: Used in the production of active pharmaceutical ingredients (APIs) for antiviral, anticancer, and antibacterial drugs.
• Glycoconjugate Vaccine Development: For the chemical conjugation of carbohydrate antigens to carrier proteins.
• Glycomimetics & Drug Design: Building block for creating synthetic sugar analogs that mimic natural carbohydrates for therapeutic applications.
• Biochemical Probes: Synthesis of labeled sugars and probes for studying biological recognition and signaling pathways.
• Academic & Industrial R&D: Fundamental reagent in carbohydrate chemistry laboratories for method development and novel compound synthesis.

Basic Information

Product Name	3,4,6-Tri-o-Acetyl-2-Azido-2-Deoxy-β-D-Glucopyranosyl Trichloroacetimidate
CAS No.	94715-57-8
Molecular Formula	C14H17Cl3N4O8
Molecular Weight	475.66 g/mol
Synonyms	2-Azido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl trichloroacetimidate; 2-Azido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosyl trichloroacetimidate; β-D-Glucopyranosyl, 2-azido-2-deoxy-3,4,6-tri-O-acetyl-, trichloroacetimidate; Glucosyl Trichloroacetimidate Derivative; Glycosyl Donor 94715-57-8; TCAI Glycosyl Donor; Trichloroacetimidate Glycosylation Reagent
EINECS	Contact for details

Quality Control

Our 3,4,6-Tri-o-Acetyl-2-Azido-2-Deoxy-β-D-Glucopyranosyl Trichloroacetimidate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.