Description

5,6-o-Isopropylidene-L-Gulonic Acid-1,4-Lactone is a key chiral intermediate and protected form of L-gulonic acid. This compound is valued for its role in the synthesis of high-value fine chemicals and active pharmaceutical ingredients (APIs), particularly in the ascorbic acid (Vitamin C) pathway. It is essential for manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries requiring precise stereochemistry and high-purity building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of L-ascorbic acid (Vitamin C) and its derivatives.
• Chiral Synthesis: Used as a building block for the production of other chiral compounds and fine chemicals due to its defined stereochemistry.
• Nutraceutical Manufacturing: Employed in the production pathways for vitamin supplements and related health products.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies and enzymatic research.
• Cosmetic Ingredients: Potential intermediate in the synthesis of antioxidant compounds used in skincare formulations.
• Food Additive Synthesis: Involved in the production chain for certain food-grade antioxidants and acidulants.

Basic Information

Product Name	5,6-o-Isopropylidene-L-Gulonic Acid-1,4-Lactone
CAS No.	94697-68-4
Molecular Formula	C9H14O6
Molecular Weight	218.21 g/mol
Synonyms	5,6-O-Isopropylidene-L-gulono-1,4-lactone; L-Gulonic acid, 5,6-O-(1-methylethylidene)-, γ-lactone; 5,6-O-(1-Methylethylidene)-L-gulono-1,4-lactone; Isopropylidene-L-gulono-1,4-lactone; 5,6-O-Isopropylidene-L-gulono-γ-lactone; L-Ascorbic acid intermediate; Protected L-gulono-1,4-lactone
EINECS	Contact for details

Quality Control

Our 5,6-o-Isopropylidene-L-Gulonic Acid-1,4-Lactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, optical rotation, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.