Description

Diethyl 2-(2,2,2-Trifluoroacetyl)Succinate is a high-value fluorinated organic building block, essential for introducing the trifluoroacetyl functional group into complex molecular architectures. Its primary commercial value lies in serving as a versatile synthon for the synthesis of advanced pharmaceutical intermediates and agrochemicals. This compound is particularly critical for research and production chemists in the fine chemical, pharmaceutical, and agrochemical industries seeking to develop novel compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated motifs for improved drug efficacy and pharmacokinetics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances lipophilicity and biological activity.
• Material Science Research: Serves as a building block for developing novel fluorinated polymers and specialty chemicals with unique surface properties.
• Organic Synthesis Reagent: Employed in Michael addition reactions, condensations, and other transformations to construct complex, fluorinated carbon chains.
• Ligand and Catalyst Development: Useful in the preparation of fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Diethyl 2-(2,2,2-Trifluoroacetyl)Succinate
CAS No.	94633-25-7
Molecular Formula	C10H13F3O5
Molecular Weight	270.20 g/mol
Synonyms	Diethyl (3-oxo-4,4,4-trifluorobutanoyl)acetate; Diethyl 2-(trifluoroacetyl)butanedioate; 2-(2,2,2-Trifluoroacetyl)succinic Acid Diethyl Ester; Ethyl 2-(2-ethoxy-2-oxoethyl)-4,4,4-trifluoro-3-oxobutanoate; 3-Oxo-4,4,4-trifluorobutanoylacetic Acid Ethyl Ester; TFAS Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl 2-(2,2,2-Trifluoroacetyl)Succinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.