Description

4',4'-Dichloromercuric-2,2,2',2'-Bistilbene Tetrasulfonic Acid is a specialized organomercury compound with a unique stilbene-derived structure, primarily valued for its role as a high-affinity sulfhydryl group reagent in biochemical research and analytical chemistry. Its core value proposition lies in its ability to form stable complexes with thiols, making it an essential tool for protein structure-function studies and enzyme inhibition assays. This chemical is critically needed by research institutions, pharmaceutical R&D laboratories, and diagnostic kit manufacturers developing sensitive assays for thiol-containing biomolecules.

Application

• Biochemical Research: As a specific and potent sulfhydryl (-SH) group blocking agent for studying enzyme active sites and protein conformation.
• Analytical Chemistry: Used in the development of colorimetric and fluorometric assays for the detection and quantification of thiols (e.g., cysteine, glutathione) in biological samples.
• Pharmaceutical Development: Employed in mechanism-of-action studies for drug candidates that target thiol-dependent pathways or enzymes.
• Diagnostic Reagent Formulation: A key component in the formulation of specific reagents for clinical chemistry analyzers to measure thiol status, an important biomarker for oxidative stress.
• Protein Chemistry: Utilized for the selective modification of cysteine residues to investigate protein folding, stability, and intermolecular interactions.
• Material Science Research: Potential application in surface functionalization and the creation of mercury-based coordination polymers or sensors due to its multiple sulfonic acid groups and mercury centers.

Basic Information

Product Name	4',4'-Dichloromercuric-2,2,2',2'-Bistilbene Tetrasulfonic Acid
CAS No.	94613-70-4
Molecular Formula	C28H18Cl2Hg2O12S4
Molecular Weight	Contact for details
Synonyms	Bistilbene Tetrasulfonic Acid, Dichloromercuric Derivative; 4,4'-Bis(chloromercuri)-2,2'-stilbenedisulfonic Acid (related structure); Mercury, dichloro[4,4'-bis[(sulfophenyl)ethenyl]]bis-, Tetrasodium Salt (possible salt form); DCMBTS; Thiol-Reactive Mercury Stilbene Dye; Organomercury Fluorescent Probe; Bis(chloromercuri)stilbenedisulfonate; SH-group specific reagent.
EINECS	Contact for details

Quality Control

Our 4',4'-Dichloromercuric-2,2,2',2'-Bistilbene Tetrasulfonic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes rigorous analytical testing, including purity assay by HPLC and confirmation of structure and functional groups by spectroscopic methods (IR, NMR). A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Mercury Content (Titration)	Conforms to theoretical value

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.