Description

3-Methylether-Estradiol is a synthetic estrogen derivative, specifically the 3-methyl ether of estradiol. This compound is of significant interest in pharmaceutical research and development, serving as a key intermediate or reference standard. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of hormone-based therapies and analytical method validation.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of more complex steroidal drugs and hormone analogs.
• Biochemical Research: Used as a reference standard or tool compound in studies investigating estrogen receptor binding, metabolism, and signaling pathways.
• Analytical Standard: Employed in quality control laboratories for method development and validation in HPLC, GC, or LC-MS analyses of steroidal compounds.
• Academic Research: Utilized in university and institutional labs for fundamental research in endocrinology and medicinal chemistry.

Basic Information

Product Name	3-Methylether-Estradiol
CAS No.	94535-16-7
Molecular Formula	C19H26O2
Molecular Weight	286.41 g/mol
Synonyms	3-Methoxyestra-1,3,5(10)-trien-17β-ol; 3-Methoxy-17β-estradiol; 17β-Estradiol 3-methyl ether; Estra-1,3,5(10)-trien-3-ol, 17β-hydroxy-, 3-methyl ether; 3-ME-E2
EINECS	Contact for details

Quality Control

Our 3-Methylether-Estradiol is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity (HPLC), identity (IR, NMR), and related substances are available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.