Description

(2'S,3R,3'Ar,5'S,7S,7'As,9Bβ)-Icosahydro-2',5'-Dihydroxy-3Aα,4',4',5Aβ,7'A,9Aα-Hexamethyl-3α-(1-Methylethyl)Spiro[7H-Benz[E]Indene-7,1'-[1H]Inden]-6-One is a complex, high-purity steroidal spiro compound characterized by its unique polycyclic framework and specific stereochemistry. This compound serves as a critical advanced intermediate or reference standard in the synthesis of novel pharmaceuticals and bioactive molecules, particularly in steroid-based drug discovery. It is essential for research and development laboratories in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise molecular scaffolds for biological activity studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-derived therapeutics targeting hormone receptors.
• Research & Development: Used as a reference standard or starting material in medicinal chemistry for structure-activity relationship (SAR) studies.
• Biochemical Research: Potential ligand or probe for investigating steroid hormone pathways and enzyme interactions in vitro.
• Fine Chemical Synthesis: Serves as a sophisticated chiral template for constructing complex natural product analogs and specialty chemicals.
• Academic Research: Valuable compound for universities and research institutes studying organic synthesis methodologies and stereochemistry.

Basic Information

Product Name	(2'S,3R,3'Ar,5'S,7S,7'As,9Bβ)-Icosahydro-2',5'-Dihydroxy-3Aα,4',4',5Aβ,7'A,9Aα-Hexamethyl-3α-(1-Methylethyl)Spiro[7H-Benz[E]Indene-7,1'-[1H]Inden]-6-One
CAS No.	94511-18-9
Molecular Formula	C30H48O3
Molecular Weight	456.71 g/mol
Synonyms	Spiro[7H-Benz[E]Indene-7,1'-[1H]Inden]-6-One, Icosahydro-2',5'-dihydroxy-3Aα,4',4',5Aβ,7'A,9Aα-hexamethyl-3α-(1-methylethyl)-, (2'S,3R,3'Ar,5'S,7S,7'As,9Bβ)-; Steroidal Spiro Ketone; Advanced Steroid Intermediate; CAS 94511-18-9.
EINECS	Contact for details

Quality Control

Our (2'S,3R,3'Ar,5'S,7S,7'As,9Bβ)-Icosahydro-2',5'-Dihydroxy-3Aα,4',4',5Aβ,7'A,9Aα-Hexamethyl-3α-(1-Methylethyl)Spiro[7H-Benz[E]Indene-7,1'-[1H]Inden]-6-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support compliance with cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.