Description

Diethyl 2,4,6-Trimethylphenyl Malonate is a high-purity, synthetically valuable malonate ester derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the development of pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the sterically hindered 2,4,6-trimethylphenyl group into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring sterically hindered aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the mesitylene moiety imparts specific biological activity and stability.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and performance materials like liquid crystals and organic electronic components.
• Organic Synthesis Reagent: Employed in Claisen condensation and other carbon-carbon bond-forming reactions to create complex esters and carboxylic acid derivatives.
• Research & Development: A valuable tool in academic and industrial R&D for methodological studies and the exploration of new chemical entities.
• Polymer Modification: Potential use as a monomer or modifier in the synthesis of specialty polymers with tailored thermal and mechanical properties.

Basic Information

Product Name	Diethyl 2,4,6-Trimethylphenyl Malonate
CAS No.	94430-86-1
Molecular Formula	C16H22O4
Molecular Weight	278.34 g/mol
Synonyms	Diethyl Mesitylmalonate; Diethyl (2,4,6-Trimethylphenyl)propanedioate; Propanedioic acid, (2,4,6-trimethylphenyl)-, diethyl ester; Mesitylmalonic Acid Diethyl Ester; Diethyl 2-(2,4,6-Trimethylphenyl)malonate; Malonic acid, (mesityl)-, diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl 2,4,6-Trimethylphenyl Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.