Description

2-Aminomethyl-Isonicotinic Acid Methyl Ester is a versatile and high-value pharmaceutical intermediate and fine chemical building block. Its unique structure, featuring both an aminomethyl group and an ester functionality on a pyridine core, makes it a critical precursor for synthesizing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors. Its reliable synthesis and consistent quality are essential for downstream process development and commercial-scale production.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurological and anti-infective drug classes.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic structure.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complex formation.
• Organic Synthesis Research: A valuable reagent for constructing complex nitrogen-containing heterocycles in academic and industrial R&D settings.
• Peptidomimetic Chemistry: The aminomethyl group allows for incorporation into peptide analogs to modify biological activity and stability.

Basic Information

Product Name	2-Aminomethyl-Isonicotinic Acid Methyl Ester
CAS No.	94413-69-1
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	Methyl 2-(aminomethyl)isonicotinate; 2-(Aminomethyl)isonicotinic Acid Methyl Ester; Methyl 2-(Aminomethyl)pyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 2-(aminomethyl)-, methyl ester; Isonicotinic acid, 2-(aminomethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 2-Aminomethyl-Isonicotinic Acid Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.