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1-(Trimethylsilyl)Allyl Bromide CAS NO 94397-40-7
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CAS No.:94397-40-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(Trimethylsilyl)Allyl Bromide is a versatile organosilicon reagent featuring both a reactive allyl bromide moiety and a protective trimethylsilyl group. This compound is valued for its dual functionality, enabling it to act as a key building block in complex organic synthesis, particularly in the construction of carbon-carbon bonds and silicon-containing frameworks. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional polymers.
Application
- Pharmaceutical Intermediates: A crucial building block for the synthesis of complex drug candidates, especially those requiring silicon incorporation or allylic functionalization.
- Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the allyl and silyl groups introduce specific biological activity or stability.
- Organosilicon Chemistry: Serves as a fundamental reagent for introducing the trimethylsilylallyl unit into molecules, useful in protecting group strategies and material science.
- Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki-Miyaura) to form new C-C bonds.
- Polymer & Material Science: Employed as a monomer or functionalization agent in the production of specialty silicones and silicon-modified polymers with tailored properties.
- Organic Synthesis Research: Utilized in academic and industrial labs for developing new methodologies involving allylation and silylation reactions.
Basic Information
| Product Name | 1-(Trimethylsilyl)Allyl Bromide |
| CAS No. | 94397-40-7 |
| Molecular Formula | C6H13BrSi |
| Molecular Weight | 193.16 g/mol |
| Synonyms | Allyltrimethylsilane Bromide; (3-Bromoprop-1-en-1-yl)trimethylsilane; Trimethyl(3-bromoallyl)silane; 3-Bromo-1-trimethylsilyl-1-propene; Allyl Bromide Trimethylsilyl Derivative; TMS-Allyl Bromide |
| EINECS | Contact for details |
Quality Control
Our 1-(Trimethylsilyl)Allyl Bromide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including GC, NMR, and Karl Fischer titration to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation. Keep away from strong acids and incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Purity (GC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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