Description

Bis(tert-Butyl) 4-Ethyl-1,4-Dihydro-2,6-Dimethylpyridine-3,5-Dicarboxylate is a high-purity, specialty dihydropyridine derivative that serves as a critical advanced intermediate in complex organic syntheses. Its value lies in the strategic protection of the dicarboxylate groups with tert-butyl moieties, which provides enhanced stability and selectivity for subsequent chemical transformations. This compound is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries, particularly for constructing complex molecular architectures in drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs), especially those based on the dihydropyridine scaffold.
• Chemical Research & Development: Used as a protected intermediate in multi-step organic synthesis for novel compound libraries and process route scouting.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring precise molecular control.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Item	Information
Product Name	Bis(tert-Butyl) 4-Ethyl-1,4-Dihydro-2,6-Dimethylpyridine-3,5-Dicarboxylate
CAS No.	94266-08-7
Molecular Formula	C20H31NO4
Molecular Weight	349.47 g/mol
Synonyms	4-Ethyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid di-tert-butyl ester; Di-tert-butyl 4-ethyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 1,4-Dihydro-4-ethyl-2,6-dimethyl-3,5-pyridinedicarboxylic acid bis(1,1-dimethylethyl) ester; Hantzsch Ester derivative; DHP derivative; tert-Butyl DHP ester
EINECS	Contact for details

Quality Control

Our production of Bis(tert-Butyl) 4-Ethyl-1,4-Dihydro-2,6-Dimethylpyridine-3,5-Dicarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.