Description

Ethyl 2-Nitro-3-Phenyl-L-Alaninate is a chiral, non-proteinogenic amino acid ester derivative. This compound serves as a crucial synthetic intermediate in the development of complex organic molecules, particularly in pharmaceutical research. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for applications such as peptide mimetics and chiral catalyst synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Chiral Synthesis: Used in asymmetric synthesis to introduce the L-phenylalanine-derived chiral center into target molecules.
• Peptidomimetics Research: Employed in medicinal chemistry for the design and construction of peptide mimetics with enhanced stability or biological activity.
• Chemical Biology Probes: Acts as a precursor for labeled or modified amino acids used to study biological processes.
• Catalyst and Ligand Development: Serves as a starting material for synthesizing chiral ligands and organocatalysts.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory synthesis in both academic and industrial research laboratories.

Basic Information

Product Name	Ethyl 2-Nitro-3-Phenyl-L-Alaninate
CAS No.	94213-42-0
Molecular Formula	C₁₁H₁₄N₂O₄
Molecular Weight	238.24 g/mol
Synonyms	L-Phenylalanine, 2-nitro-, ethyl ester; Ethyl (2S)-2-amino-3-phenyl-2-nitropropanoate; Ethyl (S)-2-nitro-3-phenylalaninate; (S)-Ethyl 2-nitro-3-phenylpropanoate; 2-Nitro-L-phenylalanine ethyl ester; Ethyl 2-nitro-3-phenyl-(S)-alaninate; (S)-2-Nitro-3-phenylalanine ethyl ester; Alaninate, ethyl 2-nitro-3-phenyl-, L-
EINECS	Contact for details

Quality Control

Our Ethyl 2-Nitro-3-Phenyl-L-Alaninate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality systems are designed to support cGMP requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.