Description

D-Glucitol 2-(Bromoacetate) is a functionalized sugar alcohol derivative, specifically a bromoacetate ester of D-glucitol (sorbitol). This compound is a valuable chemical intermediate and building block in organic synthesis, offering a reactive bromoacetyl group tethered to a biocompatible polyol scaffold. It is primarily utilized in the pharmaceutical and bioconjugation sectors for the development of prodrugs, targeted therapeutics, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing prodrugs and active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Bioconjugation Reagent: Used for site-specific modification of proteins, peptides, and antibodies to create antibody-drug conjugates (ADCs) and diagnostic probes.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating biodegradable and biocompatible polymers with tailored properties.
• Carbohydrate Chemistry Research: Essential reagent for studying glycosylation reactions and synthesizing complex carbohydrate mimetics and glycoconjugates.
• Material Science: Used in the surface functionalization of nanomaterials and hydrogels for biomedical and sensor applications.
• Chemical Biology Tool: Employed in activity-based protein profiling (ABPP) and the development of enzyme inhibitors.

Basic Information

Item	Details
Product Name	D-Glucitol 2-(Bromoacetate)
CAS No.	94199-88-9
Molecular Formula	C8H15BrO7
Molecular Weight	303.11 g/mol
Synonyms	2-O-(Bromoacetyl)-D-glucitol; Sorbitol 2-bromoacetate; D-Sorbitol 2-(bromoacetate); 1-Deoxy-1-(bromoacetamido)-D-glucitol (tautomeric form); Bromoacetic acid D-glucitol ester; Hexitol bromoacetate derivative
EINECS	Contact for details

Quality Control

Our D-Glucitol 2-(Bromoacetate) is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.