Description

L-3-Pyridylalanine Hydrochloride is a high-purity, non-natural amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a functionalized pyridine moiety and a protected amino acid handle, enabling the construction of complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and sophisticated ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in kinase inhibitor and neurological disorder research.
• Peptide Mimetic Design: Used to incorporate a pyridylalanine residue into peptide backbones to modulate bioactivity, stability, and receptor binding properties.
• Ligand Synthesis for Catalysis: Serves as a precursor for creating chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, or plant growth regulators that require specific chiral architectures.
• Biochemical Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-protein interactions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic methodology and medicinal chemistry projects.

Basic Information

Product Name	L-3-Pyridylalanine Hydrochloride
CAS No.	93960-20-4
Molecular Formula	C8H10N2O2 • HCl
Molecular Weight	202.63 g/mol (Free base: 166.18 g/mol)
Synonyms	L-3-(3-Pyridyl)alanine hydrochloride; (S)-2-Amino-3-(3-pyridyl)propionic acid hydrochloride; 3-Pyridyl-L-alanine HCl; β-(3-Pyridyl)-L-alanine hydrochloride; L-β-(3-Pyridyl)alanine hydrochloride; (S)-3-(Pyridin-3-yl)alanine hydrochloride; 3-PAL-OH • HCl
EINECS	Contact for details

Quality Control

Our L-3-Pyridylalanine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and cGMP (current Good Manufacturing Practice) starting material applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.