Description

Estra-1,3,5(10)-Triene-3,17-Diol 17-(Hydrogen Succinate) is a high-purity steroid derivative, specifically a succinate ester of estradiol. This compound is a critical pharmaceutical intermediate valued for its role in the synthesis of more complex, biologically active steroid molecules. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of steroidal APIs, hormone therapies, and other advanced medicinal compounds.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of steroidal active pharmaceutical ingredients (APIs).
• Hormone Therapy Research: Used in the development and study of novel estrogen analogs and hormone replacement therapies.
• Steroid Conjugate Synthesis: Serves as a precursor for creating steroid-protein conjugates used in immunoassays and diagnostic applications.
• Academic & Industrial R&D: Employed in chemical and pharmacological research to explore structure-activity relationships of steroid molecules.
• Process Development: Utilized in scaling up and optimizing manufacturing processes for steroidal drugs under GMP conditions.

Basic Information

Product Name	Estra-1,3,5(10)-Triene-3,17-Diol 17-(Hydrogen Succinate)
CAS No.	93939-81-2
Molecular Formula	C22H28O5
Molecular Weight	372.46 g/mol
Synonyms	Estradiol 17-Hemisuccinate; 17β-Estradiol 17-Hemisuccinate; Estradiol Hemisuccinate; E2-17-HS; Oestradiol 17-Hemisuccinate; 3,17β-Dihydroxyestra-1,3,5(10)-trien-17-yl hydrogen succinate; Estra-1,3,5(10)-triene-3,17β-diol 17-hemisuccinate
EINECS	Contact for details

Quality Control

Our Estra-1,3,5(10)-Triene-3,17-Diol 17-(Hydrogen Succinate) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.