Description

(R)-2-Benzyl-5-Pentenoic Acid is a chiral, non-racemic carboxylic acid derivative featuring a benzyl group and a terminal alkene functionality. This compound is a crucial chiral building block and intermediate in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and drug development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of cardiovascular and central nervous system (CNS) drugs.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to construct stereogenic centers with high enantiomeric purity.
• Peptidomimetics Research: Serves as a building block for the design and synthesis of peptide analogs and peptidomimetics in medicinal chemistry.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for use in enantioselective transformations.
• Fine Chemical Synthesis: A versatile intermediate for the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	(R)-2-Benzyl-5-Pentenoic Acid
CAS No.	93780-04-2
Molecular Formula	C₁₂H₁₄O₂
Molecular Weight	190.24 g/mol
Synonyms	(R)-2-Benzylpent-4-enoic acid; (R)-2-Benzyl-4-pentenoic acid; (2R)-2-Benzyl-5-pentenoic acid; (R)-2-(Phenylmethyl)-4-pentenoic acid; (R)-α-Benzyl-δ-vinylbutyric Acid; (R)-Benzylpentenoic Acid; (R)-2-Benzylidenepent-4-enoic acid (tautomer); (R)-enantiomer of 2-Benzyl-5-pentenoic acid
EINECS	Contact for details

Quality Control

Our (R)-2-Benzyl-5-Pentenoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure high chemical and optical purity. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.