Description

Hydroxy-Peg1-Methyl Ester CAS NO 93673-82-6 is a versatile polyethylene glycol (PEG) derivative, specifically a monomethyl ether of a short-chain PEG unit with a terminal hydroxyl group. This bifunctional structure, featuring both a reactive hydroxyl and a stable methyl ester, makes it a valuable building block and linker molecule in advanced organic synthesis. It is primarily utilized by pharmaceutical, bioconjugation, and specialty chemical industries for modifying molecules to enhance solubility, stability, or to create functionalized intermediates.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs, drug conjugates, and to improve the pharmacokinetic properties of active pharmaceutical ingredients (APIs).
• Bioconjugation Linker: Serves as a spacer or linker for attaching dyes, probes, or therapeutic agents to proteins, antibodies, or other biomolecules.
• Polymer Chemistry: Acts as a monomer or initiator in the synthesis of functionalized PEG-based polymers, hydrogels, and co-polymers.
• Surface Modification: Employed to create hydrophilic coatings on materials and nanoparticles to improve biocompatibility and reduce non-specific binding.
• Cross-linking Agent: Utilized in the preparation of cross-linked networks for controlled release systems and matrix materials.
• Chemical Synthesis Building Block: Provides a protected or functional handle for further chemical transformations in multi-step synthetic routes.

Basic Information

Product Name	Hydroxy-Peg1-Methyl Ester
CAS No.	93673-82-6
Molecular Formula	C4H8O4
Molecular Weight	120.10 g/mol
Synonyms	2-(2-Methoxyethoxy)acetic acid methyl ester; Ethylene glycol monomethyl ether acetate, methylated; Methyl 2-(2-methoxyethoxy)acetate; PEG-1 methyl ether acetate; Methoxy-PEG1-methyl ester; 2-(2-Methoxyethoxy)ethyl acetate; Hydroxy-terminated PEG1 methyl ester; Methyl glycolate ethylene glycol methyl ether
EINECS	Contact for details

Quality Control

Our Hydroxy-Peg1-Methyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.