Description

5-Oxaspiro[3.4]Octan-8-One is a high-purity, versatile spirocyclic lactone building block of significant interest in advanced organic synthesis. Its unique bridged bicyclic structure containing both an ether and a ketone functional group makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Serves as a core building block for creating new generations of herbicides, fungicides, and insecticides with complex, bioactive spirocyclic motifs.
• Material Science Research: Used in the development of specialty polymers, ligands for catalysis, and advanced organic frameworks due to its rigid, three-dimensional structure.
• Asymmetric Synthesis: Employed as a starting material or chiral auxiliary in stereoselective reactions to introduce quaternary carbon centers.
• Fragrance & Flavor Chemistry: Potential intermediate for synthesizing novel musk-like or other complex odorant molecules.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects.

Basic Information

Product Name	5-Oxaspiro[3.4]Octan-8-One
CAS No.	93641-55-5
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	8-Oxaspiro[4.3]octan-1-one; 1-Oxaspiro[3.4]octan-8-one; Spiro[3.4]octane-8-one, 5-oxa-; Tetrahydro-4H-spiro[furan-2,1'-cyclopropane]-4-one; 5-Oxaspiro[3.4]octan-8-one; Oxaspirooctanone
EINECS	Contact for details

Quality Control

Our 5-Oxaspiro[3.4]Octan-8-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support custom purity specifications to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.