Description

(S)-(+)-1-Cyclohexylethyl Isocyanate is a high-purity, chiral isocyanate building block essential for the synthesis of sophisticated organic molecules. Its value lies in the introduction of a chiral cyclohexylethyl moiety, enabling the creation of compounds with specific stereochemistry and enhanced biological or material properties. This product is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as chiral ligand synthesis and polymer modification.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with defined stereocenters for improved efficacy and reduced side effects.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where the specific spatial orientation of the molecule can be crucial for its biological activity and environmental profile.
• Chiral Ligand & Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Advanced Material Monomers: Incorporated into specialty polymers, such as polyurethanes and polyureas, to impart unique chiral, mechanical, or solubility properties to the final material.
• Peptidomimetics & Bio-conjugation: Facilitates the creation of peptide analogs (peptidomimetics) and is used in bioconjugation chemistry to attach functional groups to biomolecules.
• Custom Synthesis & Contract Research: An invaluable tool for custom synthesis houses and R&D laboratories focused on developing novel chemical entities for client projects.

Basic Information

Product Name	(S)-(+)-1-Cyclohexylethyl Isocyanate
CAS No.	93470-27-0
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	(S)-1-Cyclohexylethyl isocyanate; (S)-(+)-1-Cyclohexylethyl isocyanate; (S)-α-Methylcyclohexanemethyl isocyanate; (+)-(S)-1-Isocyanato-1-cyclohexylethane; (S)-1-Isocyanato-1-cyclohexylethane; (1S)-1-(Isocyanatomethyl)-1-cyclohexylethane; (S)-1-Cyclohexyl-1-ethyl isocyanate
EINECS	Contact for details

Quality Control

Our (S)-(+)-1-Cyclohexylethyl Isocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon). Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed and handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.