Description

(R)-1-Cyclohexylethyl Isocyanate is a high-purity, chiral isocyanate building block essential for the synthesis of advanced pharmaceutical intermediates and specialty polymers. Its enantiomerically pure structure provides a critical stereocenter for creating active compounds with targeted biological activity. This product is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel therapeutics and performance chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Serves as a reactive monomer for introducing cyclohexyl groups into polyurethanes and polyureas, enhancing chemical resistance and thermal stability.
• Chiral Ligand & Catalyst Development: Building block for creating novel asymmetric catalysts and chiral auxiliaries used in stereoselective synthesis.
• Peptide Mimetics & Bioconjugation: Used to introduce hydrophobic, chiral moieties into peptide backbones or for labeling biomolecules.
• Advanced Material Research: Employed in R&D for liquid crystals, specialty coatings, and high-performance adhesives requiring specific stereochemistry.

Basic Information

Product Name	(R)-1-Cyclohexylethyl Isocyanate
CAS No.	93470-26-9
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	(R)-(-)-1-Cyclohexylethyl isocyanate; (R)-1-Isocyanato-1-cyclohexylethane; (R)-α-Methylcyclohexanemethyl isocyanate; (R)-CEIC; (1R)-1-(Isocyanatoethyl)cyclohexane; (R)-1-Cyclohexyl-1-ethyl isocyanate
EINECS	Contact for details

Quality Control

Our (R)-1-Cyclohexylethyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Keep away from heat, open flames, and sources of ignition. Isocyanate compounds should be stored separately from alcohols, amines, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.