Description

19-o-Methyl-21-o-Acetyl-21-o-De(3-Carboxy-1-Oxo-2-Propenyl)-2-Demethyl-2-Methoxy-24-Methylhygrolidin is a complex, semi-synthetic macrolide derivative of interest for advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and study of novel bioactive molecules, particularly within the antibiotic and antifungal domains. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and pharmacology.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel macrolide antibiotics with potentially improved efficacy or reduced resistance.
• Medicinal Chemistry Research: Used as a reference compound or precursor in structure-activity relationship (SAR) studies to optimize biological activity.
• Antimicrobial Agent Development: Serves as a core scaffold for developing new agents targeting bacterial and fungal pathogens.
• Biochemical Tool Compound: Utilized in microbiological and enzymatic assays to investigate mechanisms of action and resistance.
• Process Chemistry & Scale-Up: Employed in the development and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Provides a high-purity benchmark for quality control (QC) and analytical method development (e.g., HPLC, LC-MS) in API manufacturing.

Basic Information

Product Name	19-o-Methyl-21-o-Acetyl-21-o-De(3-Carboxy-1-Oxo-2-Propenyl)-2-Demethyl-2-Methoxy-24-Methylhygrolidin
CAS No.	93460-68-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	19-O-Methyl-21-O-acetyl-21-O-de(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methylhygrolidin; Hygrolidin derivative; 2-Demethyl-2-methoxy-24-methylhygrolidin derivative; Modified Hygrolidin; Semi-synthetic macrolide intermediate; Antibiotic research intermediate; CAS 93460-68-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets specifications suitable for research and development purposes. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request. Our quality system is designed to support traceability and batch-to-batch consistency, which is essential for reliable research outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.