Description

2-Hydroxy-4-Methylpyridine-3-Carbonitrile is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a hydroxyl and a nitrile group on a methylated pyridine core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its bioactive pyridine scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functional organic materials, including dyes, pigments, and electronic chemicals.
• Chemical Research & Development: A valuable building block for academic and industrial R&D focused on heterocyclic chemistry and medicinal chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Hydroxy-4-Methylpyridine-3-Carbonitrile
CAS No.	93271-59-1
Molecular Formula	C7H6N2O
Molecular Weight	134.14 g/mol
Synonyms	3-Cyano-2-hydroxy-4-methylpyridine; 4-Methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile; 2-Hydroxy-4-picoline-3-carbonitrile; 3-Cyano-4-methyl-2-pyridinol; 2-Pyridinol, 3-cyano-4-methyl-; 4-Methyl-3-cyanopyridin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-Methylpyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.