Description

(S)-(-)-3-Hydroxy-3-Methyl-4,4,4-Trichlorobutyric β-Lactone is a high-purity, chiral lactone building block of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined structure, which serves as a key precursor for the synthesis of complex, optically active molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific stereochemistry for efficacy.
• Agrochemical Synthesis: Used in the research and development of advanced, stereoselective pesticides and herbicides.
• Fine Chemical Production: Serves as a versatile building block for creating complex natural product analogs and specialty chemicals.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic methodologies.
• Polymer Chemistry: Can be utilized as a monomer for the synthesis of specialized, functional polymers.

Basic Information

Product Name	(S)-(-)-3-Hydroxy-3-Methyl-4,4,4-Trichlorobutyric β-Lactone
CAS No.	93206-60-1
Molecular Formula	C7H7Cl3O3
Molecular Weight	237.49 g/mol
Synonyms	(S)-3-Hydroxy-3-methyl-4,4,4-trichlorobutyric acid β-lactone; (3S)-3-Hydroxy-3-methyl-4,4,4-trichloro-2-oxetanone; (S)-(-)-3-Hydroxy-3-methyl-4,4,4-trichloro-β-butyrolactone; (S)-HMTBL; (S)-Trichlorolactone; (S)-3-Methyl-3-hydroxy-4,4,4-trichlorobutyrolactone; (S)-enantiomer of 93206-60-1
EINECS	Contact for details

Quality Control

Our (S)-(-)-3-Hydroxy-3-Methyl-4,4,4-Trichlorobutyric β-Lactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.