Description

n-Carbobenzyloxy-D-Serine Methyl Ester is a protected amino acid derivative widely used as a key chiral building block in organic synthesis. This high-purity compound is essential for the controlled construction of complex peptides and bioactive molecules, ensuring stereochemical integrity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemical intermediates.

Application

• Peptide Synthesis: A crucial D-configured serine derivative for the solid-phase and solution-phase synthesis of specialized peptides.
• Pharmaceutical Intermediates: Serves as a chiral synthon in the research and production of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation & Linker Chemistry: Used in the preparation of peptide-drug conjugates and biomolecule labeling due to its reactive ester and protecting groups.
• Chemical Biology Research: Employed in the study of enzyme mechanisms and protein-protein interactions by incorporating modified serine residues.
• Asymmetric Synthesis: Acts as a starting material or auxiliary for the asymmetric synthesis of non-proteinogenic amino acids and other chiral compounds.

Basic Information

Product Name	n-Carbobenzyloxy-D-Serine Methyl Ester
CAS No.	93204-36-5
Molecular Formula	C12H15NO5
Molecular Weight	253.25 g/mol
Synonyms	CBZ-D-Serine Methyl Ester; Z-D-Ser-OMe; (R)-Methyl 2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanoate; D-Serine, N-[(phenylmethoxy)carbonyl]-, methyl ester; Methyl N-carbobenzoxy-D-serinate; N-Cbz-D-serine methyl ester; NSC 334906; Methyl (R)-2-((((benzyloxy)carbonyl)amino)-3-hydroxypropanoate
EINECS	Contact for details

Quality Control

Our n-Carbobenzyloxy-D-Serine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, optical rotation for chiral integrity, and identity confirmation (IR, NMR). Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.